Rare skin diseases photos

In an effort to camouflage how the disease has eaten away the skin on his lips, nose, cheeks and eyes, Jardim wears a rudimentary orange-tinted mask, its stenciled-in right eyebrow not matching his bushy real one that remains.

Beyond skin damage and cancers, about one in five XP patients may also suffer from deafness, spastic muscles, poor coordination or developmental delays, according to the U.S.-based National Cancer Institute.

More than 20 people in this community of about 800 have XP. That's an incidence rate of about one in 40 people - far higher than the one in 1 million people in the United States who have it.

brazil rare disease photo galleryFor years, nobody could tell Jardim or the others what was afflicting them.

"The doctors I went to said I had a blood disorder. Others said I had a skin problem. But none said I had a genetic disease, " Jardim said. "It was only in 2010 that my disease was properly diagnosed."

Experts say Araras has such a high incidence rate because the village was founded by only a few families and several were carriers of the disease, so it was passed to future generations as villagers intermarried.

For instance, both of Jardim's parents were carriers of the defective gene that causes the disease, largely ensuring he would have it.

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